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Academic Journal

A concerted neuron-astrocyte program declines in ageing and schizophrenia.

  • Authors : Ling E; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. .; Department of Genetics, Harvard Medical School, Boston, MA, USA. .

Subjects: Aging*/Aging*/Aging*/metabolism ; Aging*/Aging*/Aging*/pathology ; Astrocytes*/Astrocytes*/Astrocytes*/cytology

  • Source: Nature [Nature] 2024 Mar; Vol. 627 (8004), pp. 604-611. Date of Electronic Publication: 2024 Mar 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Developmental dysregulation of excitatory-to-inhibitory GABA-polarity switch may underlie schizophrenia pathology: A monozygotic-twin discordant case analysis in human iPS cell-derived neurons.

  • Authors : Toritsuka M; Department of Psychiatry, Nara Medical University School of Medicine, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan. Electronic address: .; Yoshino H

Subjects: Twins, Monozygotic*/Twins, Monozygotic*/Twins, Monozygotic*/genetics; GABAergic Neurons/GABAergic Neurons/GABAergic Neurons/*metabolism ; Induced Pluripotent Stem Cells/Induced Pluripotent Stem Cells/Induced Pluripotent Stem Cells/*metabolism

  • Source: Neurochemistry international [Neurochem Int] 2021 Nov; Vol. 150, pp. 105179. Date of Electronic Publication: 2021 Sep 06.Publisher: Pergamon Press Country of Publication: England NLM ID: 8006959 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Suppressed prefrontal neuronal firing variability and impaired social representation in IRSp53-mutant mice.

  • Authors : Kim W; Department of Biological Sciences, KAIST, Daejeon, Republic of Korea.; Shin JJ

Subjects: Neurons*/Neurons*/Neurons*/physiology ; Schizophrenia*; Animals

  • Source: ELife [Elife] 2022 Nov 01; Vol. 11. Date of Electronic Publication: 2022 Nov 01.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Electrophysiological measures from human iPSC-derived neurons are associated with schizophrenia clinical status and predict individual cognitive performance.

  • Authors : Page SC; Lieber Institute for Brain Development, Baltimore, MD 21205.; Sripathy SR

Subjects: Electrophysiological Phenomena*; Cognition/Cognition/Cognition/*physiology ; Induced Pluripotent Stem Cells/Induced Pluripotent Stem Cells/Induced Pluripotent Stem Cells/*physiology

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Jan 18; Vol. 119 (3).Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Reduced cortical neuron number and neuron density in schizophrenia with focus on area 24: a post-mortem case–control study.

Subjects: POSTMORTEM changes; NEURONS; SCHIZOPHRENIA

  • Source: European Archives of Psychiatry & Clinical Neuroscience. Sep2023, Vol. 273 Issue 6, p1209-1223. 15p. 3 Color Photographs, 2 Charts, 2 Graphs.

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Academic Journal

Dysregulation of schizophrenia-associated genes and genome-wide hypomethylation in neurons overexpressing DNMT1.

  • Authors : Saxena S; Department of Biological Sciences, Birla Institute of Technology & Science, Pilani, Hyderabad, 500078, India.; Choudhury S

Subjects: DNA Methylation* ; Gene Expression Regulation*; DNA (Cytosine-5-)-Methyltransferase 1/DNA (Cytosine-5-)-Methyltransferase 1/DNA (Cytosine-5-)-Methyltransferase 1/*genetics

  • Source: Epigenomics [Epigenomics] 2021 Oct; Vol. 13 (19), pp. 1539-1555. Date of Electronic Publication: 2021 Oct 14.Publisher: Future Medicine Country of Publication: England NLM ID: 101519720 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons.

  • Authors : Hada K; Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, 65 Tsurumai, Showa, Nagoya, Aichi, 466-8560, Japan.; Wulaer B

Subjects: Cognition/Cognition/Cognition/*drug effects ; Corpus Striatum/Corpus Striatum/Corpus Striatum/*pathology ; GTPase-Activating Proteins/GTPase-Activating Proteins/GTPase-Activating Proteins/*genetics

  • Source: Molecular brain [Mol Brain] 2021 Jan 22; Vol. 14 (1), pp. 21. Date of Electronic Publication: 2021 Jan 22.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

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Academic Journal

Structural diverseness of neurons between brain areas and between cases.

  • Authors : Mizutani R; Department of Applied Biochemistry, Tokai University, Hiratsuka, Kanagawa, 259-1292, Japan. .; Saiga R

Subjects: Neurons* ; Schizophrenia*; Brain

  • Source: Translational psychiatry [Transl Psychiatry] 2021 Jan 14; Vol. 11 (1), pp. 49. Date of Electronic Publication: 2021 Jan 14.Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Schizophrenia-Linked Protein tSNARE1 Regulates Endosomal Trafficking in Cortical Neurons.

  • Authors : Plooster M; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, North Carolina 27599.; Rossi G

Subjects: Cerebral Cortex/Cerebral Cortex/Cerebral Cortex/*metabolism ; Endosomes/Endosomes/Endosomes/*metabolism ; Neurons/Neurons/Neurons/*metabolism

  • Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Nov 10; Vol. 41 (45), pp. 9466-9481. Date of Electronic Publication: 2021 Oct Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Genome-wide identification of the shared genetic basis of cannabis and cigarette smoking and schizophrenia implicates NCAM1 and neuronal abnormality.

  • Authors : Song W; Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China; Shanghai Key Laboratory of Psychotic Disorders, Shanghai, China.

Subjects: CD56 Antigen*/CD56 Antigen*/CD56 Antigen*/genetics ; Cannabis* ; Cigarette Smoking*/Cigarette Smoking*/Cigarette Smoking*/genetics

  • Source: Psychiatry research [Psychiatry Res] 2022 Apr; Vol. 310, pp. 114453. Date of Electronic Publication: 2022 Feb 17.Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Ireland NLM ID: 7911385 Publication Model: Print-Electronic Cited Medium:

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